Sunday, February 28, 2016

Matters of the heart - Capsule-size pacemaker may hit markets by June

Times of India - ‎16 hours ago‎
Slightly bigger than a matchstick, lighter than a two-rupee coin and wireless. Patients may get this pacemaker by the middle of this year.

Tuesday, February 23, 2016

Jury in Missouri orders pharmaceutical company to pay damages to family of deceased woman who claimed talcum powder caused her ... Johnson & Johnson must pay £51 million in suit claiming Baby Powder led to ovarian cancer
Telegraph.co.uk - 11 hours ago

Sunday, February 14, 2016

Depression linked to genes inherited from Neanderthals: New study

Daily News & Analysis - ‎17 hours ago‎
WHEN MAN DID THE ORIGINAL SIN WITH NEANDERTHAL IT HAPPENED

Wednesday, February 10, 2016

LONG LIVE THE DIFFERENCE=VIVA LA DIFFERENCE

Men and women may be wired to behave differently: Study

IANS | Feb 10, 2016, 03.47 PM IST

Highlights

• Differences in the cause and progression of some diseases and disorders according to sex sometimes influence treatment of those conditions.Men and women may be wired to behave differently: Study (Getty Images)Men and women may be wired to behave differently: Study (Getty Images)ructural differences in the brain may relate to male and female behaviour differences such as men being more likely to be better at learning and performing a single task at hand and women being more likely to exhibit superior memory and social cognition skills, the study said.
Our results suggest a synchrony between sex-related differences in the brain network and behaviour," said senior study author Ragini Verma, associate professor at Perelman School of Medicine at University of Pennsylvania in the US.

The findings were published in the journal Philosophical Transactions of the Royal Society B.

Insight into brain differences between men and women offers important considerations for the growing field of personalized medicine, the study pointed out.

The findings also have potential implications for treatment of a variety of conditions.

Differences in the cause and progression of some diseases and disorders according to sex sometimes influence treatment of those conditions. For instance, men are far more likely to get autism than women are.

For the study, the researchers performed diffusion tensor imaging (DTI) brain scans and administered a computerised neurocognitive battery (CNB) of tests on 900 randomly selected healthy and unmedicated children and young adults between ages eight and 22 years.

These methods allowed the team to develop a structural connectome, akin to a road map of each participant's brain.

According to findings of the team, stronger structural connectivity in motor, sensory, and executive functions matched higher motor and spatial skills in males.

In females, subnetworks associated with social cognition, attention and memory tasks had higher connectivity and matched improved memory and social cognition skills.

Viva La Difference

09/25/2012 01:23 pm ET | Updated Nov 25, 2012
There are those who insist that men and women are alike, but I've lived long enough to know with certainty that they are not.
To start, men and women argue differently. If a woman is angry at her girlfriend she chooses her words carefully, and bends over backwards to avoid hurting her friend's feelings. But if their argument escalates to screaming or crying, they both know, without doubt, that the relationship is over, and forgiveness is not even an option.
Men, on the other hand, become provoked into arguing at the drop of a Frito. Playful rough-housing can escalate to shoving and punches, which often leads to name calling, such as Idiot, Lame-brain, Fatso and worse. Then they sit down, throw back a few beers, watch a ball game on TV and don't even remember that only seconds ago they were fighting.
Women don't get it.
I marvel when I watch men in a restaurant. The check comes, one of them looks at it and reports the total. Then they each reach into their pocket, toss a fist full of bills onto the table, get up and leave. Not one of them pauses to see whether or not they've left too much or even enough.
Women, on the other hand, know in advance that the bill will be split evenly. When the check comes the woman with the best math skills spends fifteen minutes, with paper and pen, calculating the total, tip included, after which each woman discusses who's paying cash, who's using their credit card and who definitely doesn't mind leaving the extra nickle toward the tip.
And driving? Men get nervous every time a woman's hand leaves the wheel to apply lipstick or search for tissues in her purse. But when a man's behind the wheel, he sees nothing wrong with reaching into the back seat for a map, programing his cell phone or inspecting nose hairs in the visor mirror while traveling 75 mph on the New Jersey Turnpike.
A man will refer to a women as a pack rat because she is emotionally attached to things, such as her childhood collection of Barbie dolls, Valentines she received in grammar school and every book and magazine she's ever read. Barely a week passes without him pressing for her to get rid of her dust collectors to free up space in the house.
But a man views his own accumulation of stuff as important and necessary. He has an endless assortment of hammers, screw drivers, batteries, drill tips, and battery chargers, three shoe boxes of screws, nuts, nails and bolts, and a collection of obsolete Pac-Man, Mario Brothers and Donkey Kong video games. There's also a piece-of-junk car, on blocks, that he's going to make run again one day, and enough cardboard to house 97 homeless people on the streets of Manhattan.

A man will spend hours marveling at the wonders of his incredibly expensive, highly technical camera and gloat over its countless capabilities and the exquisitely beautiful photographs it produces. A woman will drive to the nearest market, purchase an eight dollar disposable camera, take pictures, and be perfectly happy with the results.
A man can be ready to travel even before he even knows the destination. He rolls up a pair of dress slacks, a pair of jeans, four shirts, underwear, socks, a razor and a toothbrush. He only needs the shoes he's wearing.
A woman must try on every piece of clothing in her closet to see what still fits. She feels the need to be prepared with sandals, pumps, beach shoes, walking shoes, dancing shoes, hair dryer, curling iron, underwear, a lifetime supply of hair spray, mousse, gel and makeup, a different outfit and matching sweaters for every day she'll be away. When she returns home, three quarters of what she brought with her will not have been touched.
A man and woman go on a date. At the end of the evening he says he'll call her. She thinks he means tomorrow. What he actually means is, before he dies.

Real Men Want Real Love - Huffington Post

www.huffingtonpost.com/.../real-men-want-real-love_b_8276990.html
Oct 12, 2015 - Women are more likely to believe in the Prince Charming story, in which the prince will come along at the perfect time. That's why ... Ask single men what they really want, and they say love, not sex. ... Viva la difference! Men ...

Sex and brains: Vive la différence! - The Economist

www.economist.com/.../21591157-new-technique-has-drawn-wiring-dia...
Dec 7, 2013 - Vive la différence! ... MEN and women do not think in the same ways. ... Sex differences in brains—those visible to this technique, at least—thus ...

Why Do Boys Dress as Warriors and Girls as Princesses? It ...

www.yesmagazine.org/.../why-do-boys-dress-as-warriors-and-girls-as-pri...
Jan 6, 2016 - Stories do not just develop children's literacy; they convey values, beliefs, ... and their roles into those that mirrored present-day roles that men and women take on. .... Viva la difference, even if it isn't PC nowadays. Miriam Hamsa. People who write articles like this never had several children of each sex.

The science of magnetism | Attraction | Lifestyle | The ...

www.independent.co.uk › Lifestyle › Love & Sex › Attraction
Sep 11, 2008 - What, precisely, makes an attractive woman or man? ... the usual gender difference was found, in that men said they would .... VIVE LA DIFFERENCE. So what can we do to make ourselves more attractive to the opposite sex?


Funny Differences Between Genders

The Differences Between Genders

Will and Guy have discovered that the difference between men and women is not only physiological; there are many other gender differences and several of them are amusing. We say, 'Vive la différence.'
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7 Funny Gender Differences in RelationshipsGender Differences in Relationships

Amusing communication differences between men and women.
  1. Bathrooms
  2. Eating out
  3. Nicknames
  4. Cats
  5. Future
  6. Success
  7. Marriage

1) Bathrooms:

A man has six items in his bathroom: toothbrush and toothpaste, shaving cream, razor, a bar of soap, and a towel from Tesco.
The average number of items in the typical woman's bathroom is 337. [A man would not be able to identify more than 20 of these items.]

2) Eating out:

When the bill arrives, Russell, John and Trevor will each throw in £20, even though it's only for £32.50. None of them will have anything smaller and none will actually admit they want change back.
When the girls get their bill, out come the pocket calculators.

3) Nicknames:Funny nicknames

If Claire, Louise and Hannah go out for lunch, they will call each other Claire, Louise and Hannah.
If Russell, John and Trevor go out, they will affectionately refer to each other as Jackson, Parrot-face and TC [Top Cat - from the 1970's television cartoon series].

4) Cats:

Women love cats.
Men say they love cats, but when women aren't looking, men kick cats.

5) Future:

A woman worries about the future until she gets a husband.
A man never worries about the future until he gets a wife.

6) Success: Funny His and Hers

A successful man is one who makes more money than his wife can spend.
A successful woman is one who can find such a man.

7) Marriage:

A woman marries a man expecting he will change, but he doesn't.
A man marries a woman expecting that she won't change, but she does.
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Thought for Today:

What do men and beer bottles have in common?
They are both empty from the neck up.

Arguments:
A woman has the last word in any argument.
Anything a man says after that is the beginning of a new argument.

True Mates - Gender Differences

Julie didn't come home one night.  When Tom asked her where she'd been she said she spent the night at a girl friend's house.
Tom was a bit suspicious she'd been "rooting around" so rang her ten closest friends, but none of them had seen her.
The following week Tom didn't come home one night. Julie asks him where he'd been.  So Tom says he got a bit drunk at a mate's place and thought it was safer not to drive but crash out there.
Julie thinks he's been "rooting around" so rings his ten best mates.
In true male style - eight of them say he spent the night there and two claim he's still there.

Men and Women Shopping!

Men and women shopping
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The Difference Between Genders

It's fascinating to see communication differences between men and women.  Incidentally, the correct word here is indeed gender, this has everything to do with masculinity and femininity and nothing to do with sex.

10 Recommendations Made By Men to Women

  1. Don't tell anyone we can't afford a new car. Tell them we don't want one.
  2. Please don't drive when you're not driving.
  3. When the waiter asks if everything's okay, a simple 'Yes' is fine.
  4. What do you mean, "leering?" She's obstructing my view.
  5. When I'm turning the wheel and the car is heading for the slip road, saying, 'Oh, this is our exit, dearest,' is not really necessary.
  6. When you're not around, I belch so loudly that I even appal myself.
  7. "Sports Report" starts at 5pm on a Saturday and runs for one hour. This is an excellent time for you to pay bills, put laundry in the dryer, or talk to your mother.
  8. If we see each other in the morning and at night, why phone me at work?
  9. You probably don't want to know what I'm thinking about.
  10. Never buy a "new" brand of beer because 'it was on sale.'Father Son Shopping

Dress Sense - Polarises Gender Differences

A woman will dress up to go shopping, water the plants, empty the garbage, answer the phone, read a book, get the mail.
A man will dress up for weddings, funerals.
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More Amusing Gender Observations and Jokes
Have a Laugh with Will and Guy - or at Least a Smile

How To Show a Girl a Good Time

To impress his date, Randy, a young man, took her to a very posh Italian restaurant in Greenwich Village.
After sipping some fine wine, he picked up the menu and ordered. 'We'll have the Giuseppe Spomdalucci,' he said.
'Sorry, sir,' said the waiter. 'That's the owner.'

What Price A Good Woman?Male Female Gender Differences

In East Windsor Hospital in Connecticut, USA, the relatives gathered in the waiting room as their family member lay gravely ill.
Finally, the doctor came in looking tired and sombre. 'I'm afraid I am the bearer of bad news,' he said as he surveyed the worried faces, 'The only hope left for your loved one at this time is a brain transplant. It's an experimental procedure, semi-risky, and you will have to pay for the brain yourselves.'
The family members sat silently as they absorbed the news. After a few minutes, one asked, 'Well, how much does a brain cost?'
The doctor responded quickly, '$50,000 for a male brain, and $2,000 for a female brain.' [£32,500 GBP - £13000 GBP]
The moment turned awkward. The men in the room tried not to smile, avoiding eye contact with the women, but some actually smirked. One man, unable to control his curiosity, blurted out the question everyone wanted to ask, 'Why is the male brain so much more than the female brain?'
The doctor smiled at the childish innocence and then replied to the entire group, 'It's just standard pricing procedure. We have to mark down the price of the female brains, because they've been used.'

Memory Tests

  1. Men forget everything; women remember everything. That's why men need instant replays in sports because they've already forgotten what happened.
  2. Any married man should forget his mistakes. There's no use in two people remembering the same thing.
  3. A woman knows all about her children. She knows about dentist appointments and soccer games and romances and best friends and favourite foods and secret fears and hopes and dreams.  A man is vaguely aware of some small people living in the house.
  4. If your wife and a lawyer were drowning and you had to choose, would you go to lunch or to a movie?

Book of the Week:

My wife suggested that a good book for me to read to enhance our relationship. The title is, "Women are from Venus, Men are Wrong."
»

How To Help Around The House

Philip was enjoying the second week of a two-week vacation the same way he had enjoyed the first week: by doing as little as possible.
He ignored his wife Paula's not-so-subtle hints about completing certain jobs around the house, but Philip didn't realize how much this bothered her until the clothes dryer refused to work, the iron shorted and the sewing machine motor burned out in the middle of a seam. The final straw came when she plugged in the vacuum cleaner and nothing happened.
Paula looked so stricken that I had to offer some consolation.
'That's OK, darling,' Philip said. 'You still have me.'
Paula looked up at him with tears in her eyes. 'Yes, Philip,' she wailed, 'but you don't work either.'
 

How To Show Consideration For The Good Woman

Two married friends, Ross and Allan went on a drinking binge together and Ross started his tale of woe.
He said, 'Whenever I go home late at night after spending some time with my friends at a bar, I turn the headlights and engine off before and coast the car in my garage very, very silently. I sneak up the stairs only after taking off my shoes and ease very slowly in bed. Still, my wife wakes up and all hell breaks loose as she starts shouting g at me for drinking and for being out so late.'
Allan gave Ross a long meaningful stare, shook his head, and commented, 'Mate, try my method. I screech into the driveway, slam all doors noisily, storm up the steps, throw my clothes and shoes all over the place as I undress and then jump into the bed and............my wife is always sound asleep.'

Footnote:
Please send us your funny differences between genders.
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Tuesday, February 9, 2016

now road side xerox shops may make liver?






Scientists have developed a 3D printed tissue that closely mimics the human liver's sophisticated structure and function, which could be used for patient-specific drug testing and disease modelling. Researchers said the advance could help pharmaceutical companies save time and money when developing new drugs. "We've made a tool that pharmaceutical companies could use to do pilot studies on their new drugs, and they won't have to wait until animal or human trials to test a drug's safety and efficacy on patients," said Shaochen Chen, professor at the University of California, San Diego.
Existing liver models for drug screening so far lack the complex micro-architecture and diverse cell makeup. The researchers engineered a human liver tissue model that more closely resembles the real thing - a diverse combination of liver cells and supporting cells systematically organised in a hexagonal pattern. "We've engineered a functioning liver tissue that matches what you'd see under a microscope," said Chen. "The liver is unique in that it receives a dual blood supply with different pressures and chemical constituents," said Shu Chien, professor at UC San Diego.
"Our model has the potential of reproducing this intricate blood supply system, providing unprecedented understanding of the complex coupling between circulation and metabolic functions of the liver in health and disease," said Chien. The researchers used a novel bioprinting technology, which can rapidly produce complex 3D microstructures that mimic the sophisticated features found in biological tissues. The liver tissue was printed in two steps. First, the team printed a honeycomb pattern of 900-micrometre-sized hexagons, each containing liver cells derived from human induced pluripotent stem cells.
An advantage of human induced pluripotent stem cells is they are patient-specific, which makes them ideal materials for building patient-specific drug screening platforms. Since these cells are derived from a patient's skin cells, researchers do not need to extract any cells from the liver to build liver tissue. Then, endothelial and mesenchymal supporting cells were printed in the spaces between the hexagons. The entire structure a 3X3 millimetre square, 200 micrometres thick - takes just seconds to print. This is a vast improvement over other methods to print liver models, which typically take hours.
The structure was cultured in vitro for at least 20 days. The researchers then tested the resulting tissue's ability to perform various liver functions, such as albumin secretion and urea production, and compared it to other models. They found that their model was able to maintain these functions over a longer time period than other liver models.
Their model also expressed a relatively higher level of a key enzyme that is considered to be involved in metabolising many of the drugs administered to patients. The study was published in the journal PNAS.

Cotton candy inspires tech to produce organs

IANS | Feb 10, 2016, 01.13 AM IST
Image result for COTTON CANDY SOLD
New York: Taking a cue from cotton candy machines, scientists have developed a 3D artificial capillary system that can keep living cells viable and functional for more than a week, thus paving the way for making life-sized artificial livers, kidneys, bones and other essential organs.

Leon Bellan, assistant professor of mechanical engineering at Tennessee-based Vanderbilt University, has been tinkering with cotton candy machines for years. His goal is to make fibre networks that can be used as templates to produce the cell capillary systems required to create full-scale artificial organs.

"Some people in the field think this approach is a little crazy but now, we have shown we can use this simple technique to make microfluidic networks that mimic the 3D capillary system in the human body in a cell-friendly fashion," Bellan noted in a paper that appeared in the Advanced Healthcare Materials journal.

Bellan is currently focusing on water-based gels called hydrogels, and using them as scaffolds to support cells within 3D artificial organs.

To engineer tissues that have the thickness of real organs and keep cells alive throughout the entire scaffold, the researchers must build in a network of channels that allow fluids to flow through the system, mimicking the natural capillary system. According to Bellan, his cotton-candy spinning method can produce channels ranging from three to 55 microns, with a mean diameter of 35 microns.

So far, the other approaches have only managed to create networks with microchannels larger than 100 microns, about ten times the size of capillaries. "Our experiments show that after seven days, 90% of the cells in a scaffold with perfused microchannels remained alive and functional compared to only 60-70% in scaffolds that were not perfused or did not have microchannels," Bellan wrote.