Highly Cited Hindustan Times 19h ago
Here's How IIT Madras Students Are Making Wound Healing Easier For Diabetics
Students at IIT Madras have developed a novel wound dressing material
that would help diabetic patients heal faster. The dressing material
uses graphene-based compounds
Students at IIT
Madras have developed a novel wound dressing material that would help
diabetic patients heal faster. The dressing material uses graphene-based
compounds. Wound healing in diabetic is not as rapid as compared to a
normal, healthy individual. This delayed healing or non-healed wounds
could lead to serious complications and in worse cases call for
amputations too.
In a bid to contribute to the major clinical
challenge, students at IIT Madras have come up with a new wound healing
material. The researchers said, that they were aiming to exploit the
property of graphene-based materials of improving blood vessel formation
at certain concentrations to prepare an inexpensive wound dressing. In
the animal studies conducted, the psyllium-reduced graphene oxide
nanocomposite showed emphatic results.
"We hope this is the
first step towards developing inexpensive wound dressings using
graphene-based materials for clinical use," said Vignesh Muthuvijayan,
Assistant Professor, Department of Biotechnology. The researchers used a
convex lens to focus sunlight on graphene oxide to obtain reduced
graphene oxide. "Thereafter, they loaded these reduced graphene oxide
dispersions into a plant carbohydrate polymer (psyllium) solution to
obtain wound dressing scaffolds.
The researchers used fibroblast
cells which are responsible for wound healing to evaluate the toxicity
and bioactivity of these scaffolds on the cell attachment, migration and
proliferation.
"These newly developed scaffolds provide a suitable
tissue-friendly environment for cells and subsequently improve cell
proliferation and attachment," Muthuvijayan added.
The trials and
results revealed that the normal wounds treated with the dressings
healed in 16 days as compared to 23 days in untreated normal wounds.
Similarly, diabetic wounds treated with the dressings healed in 20 days
as against 26 days in untreated diabetic wounds. "These scaffolds are
easy to prepare, inexpensive, and show excellent healing properties.
Thus, the material acts as a good wound dressing and helps in
accelerated healing of normal and diabetic wounds," he said.
Diabetes
refers to a group of diseases that result in too much sugar in the
blood (high blood glucose). The sugar spike is due to an impaired
insulin hormone, that triggers abnormal metabolism of carbohydrate and
hike in sugar levels. Your diet and nutrition can play a significant
role in managing diabetes. Here are some healthy dietary tips you should
make part of your daily regime now.
Follow a balanced diet with complex carbs: According
to Preeti Rao, Health and Wellness Coach, eating a variety of fruits
and vegetables, lean protein and good sources of fat is very essential
for diabetes management. One must avoid trans fats (also called
hydrogenated fat), processed food, and sugar and up intake of complex
carbs. Complex carbohydrates are rich in fiber and are not highly
processed like refined carbohydrates. They take longer to digest and
hence provide a sustained source of energy for a longer duration.
Include more Low GI Foods:
Glycemic Index (GI) is a relative ranking of carbohydrate in foods
according to how they affect blood glucose levels. Carbohydrates with a
low GI value (55 or less) are more slowly digested, absorbed and
metabolised and cause a lower and slower rise in blood glucose. Low GI
foods are also rich in fibre which takes the longest to digest, make you
feel fuller for a longer time and help control appetite. This could
further help in weight management. Tomato, spinach, guavas, cauliflower,
and pears are some low glycemic index foods you can choose to add to
your diet.
Avoid Sugary Drinks and Fruit Juices:
Diabetics should steer clear of aerated and sugary drinks, various
studies and reports have time and again reinforced that these drinks are
full of liquid calories and can cause major spike in the blood sugar
levels. Your can of fruit juice is not one of the healthiest substitutes
either. Fruit juices especially packaged fruit juices are loaded with
fructose that elevates the blood sugar levels. It is advisable to eat
whole fruits instead. Fruits are full of fibres, fibres take time to
metabolise and thus doesn't result in sudden surge in blood sugar
levels. Eat fruits that have a low glycemic index. Eat fruits with some
nuts and olives to balance the glycemic load.
(With inputs from PTI)