Drugs for all HIV patients not feasible’
MUMBAI:
The National Aids Control Organisation (NACO) has made it clear that
India is not ready to adhere to WHO's recent recommendation of providing
antiretroviral therapy (ART) for all HIV patients regardless of their
disease stage. Till now, in India, only those with a CD4 cell count
of less than 350 are started under the ART programme. The NACO, for the
first time in over a decade, has decided that the lifesaving
antiretroviral drugs will now be offered to even those with a slightly
higher CD4 count of 500. CD4 cell count is a crucial marker of how
aggressively the virus is destroying the body's immune system.
"We have to look into the evidence of starting ART for all. More than evidence, it is operational feasibility, finances, human resource and how the ART centres will cope with the increased load of more patients," said Dr BB Rewari, national programme officer (ART), NACO. On WHO's recommendations, he said the guidelines are never meant to be adopted immediately. "It is expected to take a year or two," he said.
With the tweaking of CD4 requirement, over 2-3lakh HIV patients, who earlier did not qualify for the free ART therapy, are likely to be brought under its ambit. Currently, only 8 lakh people in the country are on the ART programme, even though the total number of people living with HIV in India is estimated to be 21 lakh.
Physicians firmly believe that the way forward is early initiation of ART in all adults, adolescents and children with HIV. Dr George Oomen, infectious diseases specialist, said there is ample evidence to show that people who have started ART at their highest CD4 count, be it 750 or 1,000, do best.
Head of medicine at Parel's KEM Hospital Dr AR Pazare reiterated, "That is the way world is treating HIV. Why wait for the person to become too sick or for his CD4 count to fall so much?" He said early ART can not only stop progression of disease but also cut down on transmission.
Parallel to the CD4 debate is that of providing oral pre-exposure prophylaxis (PrEP) to prevent acquisition of HIV. Ashok Row Kavi of Humsafar trust, that works with men having sex with men, said PrEP has been in use in India for the last few years, but its inclusion in national programme may not be a reality soon. "There is an ideological debate on whether to provide ART to gay men as a preventive drug or first reach out to all women and kids," he added. Rewari said PrEp is being tried as a pilot study among female sex workers in Chennai, Mysore and Kolkata.
"We have to look into the evidence of starting ART for all. More than evidence, it is operational feasibility, finances, human resource and how the ART centres will cope with the increased load of more patients," said Dr BB Rewari, national programme officer (ART), NACO. On WHO's recommendations, he said the guidelines are never meant to be adopted immediately. "It is expected to take a year or two," he said.
With the tweaking of CD4 requirement, over 2-3lakh HIV patients, who earlier did not qualify for the free ART therapy, are likely to be brought under its ambit. Currently, only 8 lakh people in the country are on the ART programme, even though the total number of people living with HIV in India is estimated to be 21 lakh.
Physicians firmly believe that the way forward is early initiation of ART in all adults, adolescents and children with HIV. Dr George Oomen, infectious diseases specialist, said there is ample evidence to show that people who have started ART at their highest CD4 count, be it 750 or 1,000, do best.
Head of medicine at Parel's KEM Hospital Dr AR Pazare reiterated, "That is the way world is treating HIV. Why wait for the person to become too sick or for his CD4 count to fall so much?" He said early ART can not only stop progression of disease but also cut down on transmission.
Parallel to the CD4 debate is that of providing oral pre-exposure prophylaxis (PrEP) to prevent acquisition of HIV. Ashok Row Kavi of Humsafar trust, that works with men having sex with men, said PrEP has been in use in India for the last few years, but its inclusion in national programme may not be a reality soon. "There is an ideological debate on whether to provide ART to gay men as a preventive drug or first reach out to all women and kids," he added. Rewari said PrEp is being tried as a pilot study among female sex workers in Chennai, Mysore and Kolkata.
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